Updated: 08 Jul 2025

10 Best berberine supplements of 2025

Updated: 08 Jul 2025

#1

Best Choice

Natural Factors WellBetX Berberine 500 mg 120 Vegetarian Capsules

9.9

Natural Factors

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Main highlights

Glucose metabolism: Helps reduce the digestion of carbohydrates to limit the amount of glucose passing into the blood; Supports healthy weight management

Cardiovascular support: Delivers 500 mg of pure berberine to help maintain already healthy blood sugar and cholesterol levels; Supports healthy insulin sensitivity

A natural ingredient: Contains berberine HCl (hydrochloride) sustainably sourced from barberry root extract
#2

Best Value

Thorne Berberine 1000 mg per Serving - Botanical Supplement - Support Heart Health, Immune System, Healthy GI- Gluten-Free, Dairy-Free - 60 Capsules - 30 Servings

9.7

THORNE

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Main highlights

Optimal Wellness: Berberine provides immune function support and promotes a healthy respiratory tract

Healthy Body: Berberine is effective in helping to maintain metabolism and cholesterol levels already within a normal range

GI Support: Supports beneficial balance in the gut*
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#3

Best Naturals Berberine 500mg 120 Capsules

9.5

Best Naturals

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Main highlights

Non-GMO & Gluten Free.

500 mg of Berberine HCL per Capsule - 120 Capsules per Bottle.

3rd Party Lab Tested for Purity & Quality.
#4

Vitaceuticals Berberine+ Supplement - 500mg Berberine with Ceylon Cinnamon & Milk Thistle - Supports Metabolic Health, Liver Function, Digestive Balance & Glucose Metabolism - 60 Capsules

9.3

Vitaceuticals

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Main highlights

METABOLIC SUPPORT: Combines Berberine, Ceylon Cinnamon, and Milk Thistle to help support natural metabolic balance; ideal for active and wellness-focused lifestyles

LIVER FUNCTION: Includes Milk Thistle and Ceylon Cinnamon traditionally used to support liver health; helps maintain liver function within normal range

GLUCOSE METABOLISM: Formulated to help support healthy glucose processing and energy metabolism; part of a balanced diet and lifestyle
#5

Berberine Capsules - 5050mg Formula Pills with Black Pepper Extract - 90 Capsules Berberine Supplement for 3 Month Supply

9.2

BEBEFEN

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Main highlights

️ Our potency Berberine extract is derived from raw Berberine and combined with Black Pepper for better absorption.*

️ More Berberine = More Value & More Health Benefits - Berberine Pills contain equivalent to 5050 mg powder in each capsule.

️ (90 Day Supply | 90 Capsules | 5050mg) - We provide you with a 90 day supply for your healthy lifestyle change.
#6

(2 Packs) Berberine Supplement Plus Ceylon Cinnamon, Turmeric, Artichoke, Milk Thistle, Black Pepper - 120 Capsules - 4 Months Supply

9.1

BMVINVOL

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Main highlights

How to Take: As a dietary supplement, take one (1) capsule once daily or as directed by your healthcare professional.

All-in-One Supplement: Our product contains the most important ingredients and cuts out the fluff! Rather than taking 5 or 6 different products that only include one essential ingredient.

6-in-1: Berberine, Ceylon Cinnamon, Milk Thistle, Turmeric Root, Artichoke Leaf, Black Pepper.
#7

Ultra High Strength Berberine HCl from The Himalayas - 97% Standardized Purity - All Natural Extraction - 82:1 Concentrated Extract - The Strongest Berberine 500mg Available - 90 Veggie Capsules

8.8

Toniiq

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Main highlights

WILD HARVESTED FROM THE MINERAL-RICH FOOTHILLS OF THE HIMALAYAS: Because our Berberis Aristata is grown in the wild, only the most resilient plants (rich in active components and nutrients) make it to harvest. Toniiq Berberine is produced using an aqueous extraction process to ensure that an all-natural composition is preserved while ensuring nothing but the highest level of purity and potency in the finished product.

SETTING A NEW STANDARD FOR PURITY: To ensure that you are getting a high-quality Berberine 500mg supplement, each batch is tested for quality and purity both during and after manufacturing. Each lot is additionally tested for solvent residues, heavy metals, and toxins.

MEET THE NEXT GENERATION OF BERBERINE: Toniq Berberine is an 82x concentrated extract, bringing the most potent levels of blood sugar support in the market. Our berberine contains an unprecedented purity level of 97% (most Berberine Plus extracts, Berberine 1200mg, and AMPK Activator supplements contain 70% or less). Higher purity means a greater bioavailability of the active compounds that give berberine its powerful ability to help the body maintain healthy blood sugar metabolism.*
#8

2 Pack - Best Naturals Berberine Plus 1000mg/Serving 60 Capsules Supports Healthy Glucose Metabolism (Non-GMO) (Total 120 Capsules)

8.7

Best Naturals

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Main highlights

Supports healthy lipid levels*

Supports healthy glucose metabolism*

Supports healthy cholesterol level*
#9

New Berberine MAXIMUM POTENCY 1000mg per Serving (2 capsules 500mg each) Non-GMO, Vegan, Gluten Free. 90 Easy to Swallow Capsules

8.6

Nutrali

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Main highlights

SUPPORT WHOLE-BODY HEALTH - Each serving provides 1000mg of Berberine (500mg per capsule), Harness the power of nature

POWER PACKED PLANT EXTRACT – All-Natural Berberine is derived from plants

NON-GMO, VEGAN, GLUTEN FREE - We prioritize your well-being by ensuring our Berberine supplement is free from genetically modified organisms (GMOs), suitable for vegans, and gluten-free. Embrace a healthy lifestyle without compromise.
#10

Berberine Plus Ceylon Cinnamon | 2000mg | 120 Veggie Capsules | Vegetarian, Non-GMO & Gluten Free Supplement | Berberine Complex | by Horbaach

8.3

Horbäach

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Main highlights

SUPERIOR INGREDIENTS: Features Ceylon Cinnamon and Berberine HCl, each in premium forms

POWERFUL COMPLEX: Scientifically-designed formula combining both Berberine and Cinnamon

EXPERTLY CRAFTED: Our premium formula is backed by our commitment to purity and potency

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10 Best berberine supplements of 2025

Natural Factors WellBetX Berberine 500 mg 120 Vegetarian Capsules

9.9

Main highlights

Thorne Berberine 1000 mg per Serving - Botanical Supplement - Support Heart Health, Immune System, Healthy GI- Gluten-Free, Dairy-Free - 60 Capsules - 30 Servings

9.7

Main highlights

Best Naturals Berberine 500mg 120 Capsules

9.5

Main highlights

Vitaceuticals Berberine+ Supplement - 500mg Berberine with Ceylon Cinnamon & Milk Thistle - Supports Metabolic Health, Liver Function, Digestive Balance & Glucose Metabolism - 60 Capsules

9.3

Main highlights

Berberine Capsules - 5050mg Formula Pills with Black Pepper Extract - 90 Capsules Berberine Supplement for 3 Month Supply

9.2

Main highlights

(2 Packs) Berberine Supplement Plus Ceylon Cinnamon, Turmeric, Artichoke, Milk Thistle, Black Pepper - 120 Capsules - 4 Months Supply

9.1

Main highlights

Ultra High Strength Berberine HCl from The Himalayas - 97% Standardized Purity - All Natural Extraction - 82:1 Concentrated Extract - The Strongest Berberine 500mg Available - 90 Veggie Capsules

8.8

Main highlights

2 Pack - Best Naturals Berberine Plus 1000mg/Serving 60 Capsules Supports Healthy Glucose Metabolism (Non-GMO) (Total 120 Capsules)

8.7

Main highlights

New Berberine MAXIMUM POTENCY 1000mg per Serving (2 capsules 500mg each) Non-GMO, Vegan, Gluten Free. 90 Easy to Swallow Capsules

8.6

Main highlights

Berberine Plus Ceylon Cinnamon | 2000mg | 120 Veggie Capsules | Vegetarian, Non-GMO & Gluten Free Supplement | Berberine Complex | by Horbaach

8.3

Main highlights

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